Stability-Indicating Simultaneous Method Development and Validation of Guaifenesin and Dextromethorphan HBr by Reverse-Phase High-Performance Liquid Chromatography
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چکیده
منابع مشابه
Development and validation of stability indicating method for the determination of exemestane by reverse phase high performance liquid chromatography.
Exemestane is an aromatase inhibitor used in the treatment of breast cancer. A selective stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed which can separate and accurately quantitate low levels of exemestane. The stability-indicating capability of the method was demonstrated by adequate separation of exemestane and all the degradatio...
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Research in the many areas of human immunodeficiency virus treatment, eradication and prevention has necessitated measurement of antiretroviral concentrations in nontraditional specimen types. For HIV infection, drug combinations are typically used as highly active antiretroviral therapy, intended to maximize viral suppression. A novel four drugs combination was used, which contains two nucleos...
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A stability indicating reversed phase HPLC assay method has been used for the simultaneous assay of piracetam and cinnarizine drugs in hard gelatin capsule formulation. The separation is achieved by gradient elution using Hypersil BDS C8 column (250 mm × 4.6 mm, i.d. 5 μm particle size) with mobile phase (A) consisting of 0.015 M dipottassium hydrogen phosphate and 2 mL of triethyl amine adjust...
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An enantiomeric separation of stability-indicating high performance liquid chromatographic method was developed and validated for the analysis of orphenadrine enantiomers. The degradation behaviour of orphenadrine was investigated under different stress conditions recommended by International Conference on Harmonization (ICH). Enantiomeric resolution of the drug and complete separation from its...
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ژورنال
عنوان ژورنال: INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE
سال: 2020
ISSN: 0975-9506
DOI: 10.25258/ijpqa.11.2.13